Gerry is a talented but down-on-his-luck gambler whose fortunes begin to change when he meets Curtis, a younger, highly charismatic poker player. The two strike up an immediate friendship and Gerry quickly persuades his new friend to accompany him on a road trip to a legendary high stakes poker game in New Orleans. As they make their way down the Mississippi River, Gerry and Curtis manage to find themselves in just about every bar, racetrack, casino, and pool hall they can find, experiencing both incredible highs and dispiriting lows, but ultimately forging a deep and genuine bond that will stay with them long after their adventure is over.

Tom Sawyer and his pal Huckleberry Finn have great adventures on the Mississippi River, pretending to be pirates, attending their own funeral, and witnessing a murder.

In turn-of-the-century Mississippi, an 11-year-old boy comes of age as two mischievous adult friends talk him into sneaking the family car out for a trip to Memphis and a series of adventures.

Jessie deals with a bad breakup, by purchasing a sheet of acid to share with his friends back home in Missouri. He hopes this will erase the bad memory of his college girlfriend, delivering the heartbreaking news to him, during sex. Departing New Orleans, Jessie detours onto Route 61, seeking a change of routine from the monotony of the Interstate. Unexpectedly, his engine fails at a forgotten trailer park in Cleveland, Mississippi. Fearful he’s about to be harmed by bikers, Jessie exchanges hits of L.S.D. for safe passage home. During the ebb and flow of the day, Jessie experiences the extraordinary in the pedestrian, whilst resurrecting the lives of many. Inspired by a true misadventure.